MOv-gamma Chimeric Receptor Gene

Preferred Label : MOv-gamma Chimeric Receptor Gene;

NCIt synonyms : MOv-gamma; MOv-g;

NCIt definition : A recombinant engineered chimeric gene derived from the murine gene encoding the variable region of monoclonal antibody MOv18 against folate-binding protein, which is often overexpressed in human ovarian cancer cells, and the gene encoding the Fc receptor for the gamma subunit of human IgG and IgE. Peripheral blood lymphocytes expressing the MOv-gamma gene may be used in the immunotherapeutic treatment of ovarian cancer. (NCI04);

NSC code : 673412;

Details

Origin ID

C2638;

UMLS CUI

C0935881;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Allogeneic Lymphocytes/Interleukin-2/MOv-Gamma Chimeric Receptor Gene [NCIt concept]
- Allogeneic Lymphocytes/MOv-Gamma Chimeric Receptor Gene [NCIt concept]

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