Tucotuzumab Celmoleukin

Preferred Label : Tucotuzumab Celmoleukin;

NCIt synonyms : KSA-interleukin-2; KSA-Interleukin-2 Fusion Protein; huKS-IL2 Fusion Protein; KSA-IL-2;

NCIt definition : A recombinant fusion protein comprised of a human monoclonal antibody directed against the epithelial cell adhesion molecule (EpCAM or KS) linked to an active interleukin-2 (IL2) molecule with potential antineoplastic activity. Tucotuzumab Celmoleukin recognizes and binds to EpCAM, a cell surface epithelial protein that is expressed on a wide variety of cancer cells, thereby concentrating IL2 in EpCAM-expressing tumor tissue. Subsequently, the localized IL2 moiety of the fusion protein may stimulate a cytotoxic T-cell antitumor immune response.;

UNII : 4ON7FF680U;

CAS number : 339986-90-2;

Molecule name : EMD 273066; EMD-273066;

Details

Origin ID

C2630;

UMLS CUI

C1721369;

Currated CISMeF NLP mapping
- tucotuzumab celmoleukin [MeSH concept]
- tucotuzumab celmoleukin [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- tucotuzumab celmoleukin [MeSH concept]
- tucotuzumab celmoleukin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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