NCIt definition : A recombinant fusion protein comprised of a human monoclonal antibody directed against
the epithelial cell adhesion molecule (EpCAM or KS) linked to an active interleukin-2
(IL2) molecule with potential antineoplastic activity. Tucotuzumab Celmoleukin recognizes
and binds to EpCAM, a cell surface epithelial protein that is expressed on a wide
variety of cancer cells, thereby concentrating IL2 in EpCAM-expressing tumor tissue.
Subsequently, the localized IL2 moiety of the fusion protein may stimulate a cytotoxic
T-cell antitumor immune response.;
UNII : 4ON7FF680U;
CAS number : 339986-90-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 339986-90-2
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