NCIt definition : A semi-synthetic triterpene glycoside, derived from the naturally occurring saponins.
GPI-0100 functions as an adjuvant when given as part of a vaccine preparation to improve
the immunogenicity of antigens such as proteins, carbohydrates. GPI-0100 containing
vaccines have been used with both viral and tumor antigens to elicit a Type 1 helper
T cell response for those diseases in which a cytotoxic T lymphocyte (CTL) response
is desired.;