Preferred Label : Phosphoinositol Kinase Family Gene;
NCIt synonyms : Phosphatidylinositol Kinase Family Gene; Phosphatidylinositol Kinase Gene; Phosphoinositol Kinase Gene;
NCIt definition : Human Phosphoinositol Kinase Family Genes encode Phosphoinositol Kinases, enzymes
that phosphorylate at various positions the inositol group in membrane-bound phosphatidylinositol,
often in response to extracellular signals through G-Protein Coupled Receptors or
Receptor Tyrosine Kinases. The resultant phosphoinositides act as selective membrane
docking sites for signal transduction proteins with diverse PH domains. Phosphorylated
inositols are released as second messengers by enzymatic cleavage of the phosphoinositides.;
Origin ID : C26072;
UMLS CUI : C1335406;
Semantic type(s)
- gene_found_in_organism
- gene_plays_role_in_process
