" /> St. John's Wort - CISMeF





Preferred Label : St. John's Wort;

NCIt synonyms : Hypericum Perforatum Extract; St John's Wort;

NCIt related terms : hypericum perforatum;

NCIt definition : An herbal extract prepared from the plant Hypericum perforatum (St. John's wort) with photodynamic, antineoplastic, and antidepressant activities. Hypericin, one of the active compounds found in Hypericum perforatum, is a photosensitizer that, when exposed to a particular wavelength and intensity of light, may induce tumor cell apoptosis. Another compound, hyperforin, induces caspase-dependent apoptosis in certain tumor cell lines. Hypericum perforatum preparations may also stimulate the activity of cytochrome P450 enzymes and P-glycoprotein drug transporters, resulting in increased metabolism and decreased efficacy of various chemotherapeutic agents and other drugs.;

Alternative definition : NCI-GLOSS: An herbal product sold as an over-the-counter treatment for depression. It is being studied for its ability to lessen certain side effects of cancer treatment.;

UNII : UFH8805FKA;

CAS number : 84082-80-4;

Codes from synonyms : CDR0000044462; CDR0000044957;

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Keyword's position in hierarchy(ies) : arborescence

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08/05/2025


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