NCIt definition : The disodium salt of a synthetic form of a naturally-occurring dipeptide consisting
of L-glutamic acid and L-tryptophan with potential antiangiogenic and potential immunomodulating
activities. Oglufanide inhibits vascular endothelial growth factor (VEGF), which may
inhibit angiogenesis. This agent has also been reported to stimulate the immune response
to hepatitic C virus and intracellular bacterial infections.;
Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called angiogenesis
inhibitors.;