Interleukin-2 Gene

Preferred Label : Interleukin-2 Gene;

NCIt synonyms : IL-2 Gene;

NCIt definition : The DNA sequence that encodes the protein cytokine interleukin-2 (IL-2). When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-2 cDNA expresses IL-2 which may activate antitumoral natural killer cells and elicit an antitumoral cytotoxic T-cell response, resulting in an inhibition of tumor progression. (NCI04);

NCI Metathesaurus CUI : CL448417;

Details

Origin ID

C2549;

UMLS CUI

C0879590;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- Interleukin 2 [OMIM gene]
- interleukin 2 [HGNC gene]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Autologous Tumor Cell Vaccine/CD40-Ligand/Interleukin-2 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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