Preferred Label : Autologous Expanded Mesenchymal Stem Cells OTI-010;
NCIt synonyms : Autologous Expanded Mesenchymal Stem Cells;
NCIt related terms : Stromagen;
NCIt definition : Multipotent self-renewing adherent non-hematopoietic stromal cells harvested from
a patient's bone marrow and grown in vitro. When injected back into the patient, autologous
expanded mesenchymal stem cells OTI-010 may differentiate into various mesenchyme-derived
cell types and, in some instances, may augment bone marrow engraftment after whole-body
irradiation.;
Alternative definition : NCI-GLOSS: A product that is made of special stem cells taken from a patient's bone
marrow and grown in the laboratory. After a patient's bone marrow is destroyed by
treatment with whole body irradiation or chemotherapy, these cells are injected back
into the patient to help rebuild bone marrow. Stromagen has been studied in the prevention
of graft-versus-host disease during stem cell transplant in patients receiving treatment
for cancer. Stromagen is used in cellular therapy.;
Drug name : Stromagen;
Molecule name : OTI-010;
Codes from synonyms : CDR0000046702; CDR0000393539;
Origin ID : C2534;
UMLS CUI : C1541584;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
