Anhydrovinblastine

Preferred Label : Anhydrovinblastine;

NCIt synonyms : AVLB;

NCIt definition : A semisynthetic derivative of the vinca alkaloid vinblastine, with potential antineoplastic activity. Like vinblastine, anhydrovinblastine targets and binds to tubulin and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and causing tumor cell cycle arrest in the M phase.;

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called mitotic inhibitors.;

UNII : 5B622U08B3;

CAS number : 38390-45-3;

Codes from synonyms : CDR0000046664;

Details

Origin ID

C2526;

UMLS CUI

C0796616;

Automatic exact mappings (from CISMeF team)
- 3',4'-anhydrovinblastine [MeSH concept]
- 3',4'-anhydrovinblastine [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Microtubule Process [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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