Preferred Label : Allogeneic GM-CSF-secreting Lethally Irradiated Prostate Cancer Vaccine;
NCIt synonyms : Allogenic Prostate GVAX; GVAX Prostate; GM-CSF Gene Transduced Allogeneic Prostate Cancer Vaccine; Allogeneic Prostate Cancer Vaccine, GM- CSF Gene Transduced; Allogeneic GM-CSF Prostate Cancer Vaccine; Prostate Cancer Vaccine, GM-CSF Gene Transduced; GVAX Allogeneic Prostate Cancer Vaccine; GVAX Allogenic Prostate Cancer Vaccine; Prostate Cancer Vaccine, GVAX; GVAX Prostate Cancer Vaccine;
NCIt definition : An allogeneic whole cell vaccine expressing human granulocyte macrophage-colony stimulating
factor (GM-CSF) with potential antineoplastic activity. Tumor cells from prostate
cancer patients are harvested and then genetically modified to secrete GM-CSF, an
immune stimulatory growth factor that plays a key role in stimulating the body's immune
responses against tumor cells. Because the vaccine is derived from allogenic cells,
it has demonstrated a favorable side effect profile than other approaches of delivering
long-lasting GM-CSF.;
Origin ID : C2525;
UMLS CUI : C0796615;
Semantic type(s)
- concept_is_in_subset
