Lactate Dehydrogenase

Preferred Label : Lactate Dehydrogenase;

NCIt synonyms : Lactic Acid Dehydrogenase; L-Lactic Acid Dehydrogenase; L-( )-Lactate Dehydrogenase; EC 1.1.1.27; NAD-Lactate Dehydrogenase; LDH;

NCIt definition : A family of homotetrameric cytoplasmic enzymes involved in the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.;

Alternative definition : NCI-GLOSS: One of a group of enzymes found in the blood and other body tissues and involved in energy production in cells. An increased amount of lactate dehydrogenase in the blood may be a sign of tissue damage and some types of cancer or other diseases.;

Codes from synonyms : CDR0000354465; CDR0000354462; CDR0000354463;

Details

Origin ID

C25184;

UMLS CUI

C0022917;

Currated CISMeF NLP mapping
- L-Lactate dehydrogenase [MeSH Descriptor]
- L-Lactate dehydrogenase [MeSH concept]
- L-Lactate dehydrogenase (Cytochrome) [MeSH Descriptor]
- L-Lactate dehydrogenase (Cytochrome) [MeSH concept]
- L-lactate dehydrogenase (substance) [SNOMED CT concept]
- Lactate dehydrogenase [LOINC component]
- Lactate dehydrogenase [MedDRA LLT]
- l-lactate dehydrogenase [SNOMED Notion]
- l-lactate dehydrogenase (cytochrome) [SNOMED Notion]
- lactate dehydrogenases [MeSH Descriptor]
- lactate dehydrogenases [MeSH concept]
False automatic mappings
- Lactate dehydrogenase (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- L-Lactate dehydrogenase [MeSH concept]
- L-Lactate dehydrogenase [MeSH Descriptor]
- L-lactate dehydrogenase (substance) [SNOMED CT concept]
- Lactate dehydrogenase [LOINC component]
- Lactate dehydrogenase (substance) [SNOMED CT concept]
- l-lactate dehydrogenase [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_biochemical_function
- Oxidoreductase [NCIt concept]

Keyword's position in hierarchy(ies) :

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