Preferred Label : At 211 Monoclonal Antibody 81C6;
NCIt synonyms : Astatine 211 Conjugated 81C6 Anti-Tenascin Monoclonal Antibody; Astatine At 211 Monoclonal Antibody 81C6; Astatine-211 Labelled Anti-Tenascin Monoclonal Antibody 81C6; Astatine At 211 MOAB 81C6;
NCIt definition : A radioimmunoconjugate of a human-murine chimeric IgG2 monoclonal antibody (MoAb)
81C6 labeled with an alpha-emitting radionuclide Astatine 211 (At-211), with imaging
and radioimmunotherapeutic properties. MoAb 81C6 recognizes the extracellular matrix
antigen tenascin (hexabrachion), which is up-regulated in gliomas and other cancers.
Using MoAb 81C6 as a carrier for At-211 results in the targeted imaging and/or destruction
of cells expressing tenascin.;
Origin ID : C2490;
UMLS CUI : C0796331;
Semantic type(s)
- concept_is_in_subset
