Angiotensin-1 - CISMeF

Preferred Label : Angiotensin-1;

NCIt synonyms : AGT; Ang I; Angiotensin; Angiotensin I; Angiotensin 1-10;

NCIt definition : Angiotensin-1 (10 aa, 1 kDa) is encoded by the human AGT gene. This protein is involved in the response to lowered renal blood pressure.;

NCIt note : Angiotensinogen is cleaved by renin to form Angiotensin-1 (Angiotensin 1-10; Angiotensin I; Ang I). The removal of two C-terminal amino acids from Ang I by angiotensin-converting enzyme (ACE) releases the active peptide Angiotensin-2 (Angiotensin 1-8; Angiotensin II; Ang II). The removal of one C-terminal amino acid from Ang I by angiotensin-converting enzyme 2 (ACE) releases the active peptide Angiotensin 1-9.;

Details

Origin ID

C248;

UMLS CUI

C4521302;

Automatic exact mappings (from CISMeF team)
- Alanine-glyoxylate aminotransferase [OMIM gene]
- Angiotensin [ICHI extension code]
- Angiotensin I [MedDRA Preferred Term]
- Angiotensin I [LOINC component]
- Angiotensin I (substance) [SNOMED CT concept]
- Angiotensin I increased [MedDRA Preferred Term]
- Angiotensin II [MedDRA Preferred Term]
- Angiotensin II increased [MedDRA Preferred Term]
- Angiotensinogen [OMIM Phenotype]
- alanine--glyoxylate aminotransferase [ORDO Gene]
- amnesia, transient global [MeSH Descriptor]
- angiotensin A [MeSH Supplementary Concept]
- angiotensin A [MeSH concept]
- angiotensin I [MeSH concept]
- angiotensin I [COVID-19 Thesaurus concept]
- angiotensin i [MeSH Descriptor]
- angiotensin i [SNOMED Notion]
- angiotensin ii [SNOMED Notion]
- angiotensin iii [SNOMED Notion]
- angiotensinogen [ORDO Gene]
- trans fatty acids [MeSH Descriptor]
Currated CISMeF NLP mapping
- Angiotensin [ICD-11 Extension code]
- angiotensin [Substance BNPC]
- angiotensin, nos [SNOMED Notion]
- angiotensins [MeSH Descriptor]
- angiotensins [MeSH concept]
False automatic mappings
- Angiotensin (substance) [SNOMED CT concept]
OMIM relation
- Angiotensinogen [OMIM Phenotype]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- angiotensin iii [MeSH Descriptor]
gene_encodes_gene_product
- AGT Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_chemical_classification
- Protein Fragment [NCIt concept]
gene_product_is_element_in_pathway
- Angiotensin II Signaling Pathway [NCIt concept]
- Angiotensin-converting Enzyme 2 Pathway [NCIt concept]
- Bioactive Peptide Signaling Pathway [NCIt concept]
- Cardiac Hypertrophy Pathway [NCIt concept]
- NFAT Pathway [NCIt concept]
- Renin-Angiotensin Pathway [NCIt concept]
gene_product_is_physical_part_of
- Angiotensinogen [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]
- Metabolism, Minerals/Electrolytes [NCIt concept]
has_gene_product_element
- Angiotensin-2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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