Preferred Label : I 131 Monoclonal Antibody A33;
NCIt synonyms : Iodine I 131 Monoclonal Antibody A33;
NCIt definition : A radioimmunoconjugate of a humanized monoclonal antibody (MoAb) A33 labelled with
Iodine 131 (I-131). MoAb A33 recognizes A33 antigen, a 43 KDa transmembrane glycoprotein
of the immunoglobulin superfamily, highly and homogenously expressed in 95% of colorectal
cancers, with only restricted expression in normal colonic mucosa. Using MoAb A33
as a carrier for I-131 results in the targeted imaging and/or destruction of cells
expressed A33 antigen.;
Origin ID : C2477;
UMLS CUI : C0678093;
Semantic type(s)
- concept_is_in_subset
