Preferred Label : Monoclonal Antibody muJ591;
NCIt synonyms : muJ591 Monoclonal Antibody; MoAb muJ591;
NCIt related terms : muJ591;
NCIt definition : A murine IgG monoclonal antibody against the external domain of the prostate-specific
membrane antigen (PSMA), overexpressed in the malignant prostate and its metastases.
Although PSMA is not a biomarker of disease progression, over-expression indicates
an aggressive phenotype of the prostate cancer. Radiolabelled MoAb muJ591 may be used
in prostate cancer diagnosis and therapy.;
Alternative definition : NCI-GLOSS: A type of monoclonal antibody used in cancer detection or therapy. Monoclonal
antibodies are laboratory-produced substances that can locate and bind to cancer cells.;
Codes from synonyms : CDR0000046733;
Origin ID : C2476;
UMLS CUI : C0678086;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
