Peptide 946 Melanoma Vaccine

Preferred Label : Peptide 946 Melanoma Vaccine;

NCIt definition : A melanoma peptide vaccine with potential antineoplastic activity. Peptide 946 melanoma vaccine contains one of the peptide sequences for a melanoma-specific epitope that is recognized by melanoma-specific cytotoxic T lymphocytes (CTL). This vaccine contains a peptide sequence homologous to the native epitope and is often formulated with an adjuvant such as QS-21 or Montanide ISA-51 to boost its immune stimulation. Vaccination with peptide 946 vaccine may produce antibodies as well as elicit a cytotoxic T- lymphocyte (CTL) response against cells expressing this antigen, resulting in decreased tumor cell growth.;

Details

Origin ID

C2466;

UMLS CUI

C0677986;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Incomplete Freund's Adjuvant/Peptide 946 Melanoma Vaccine [NCIt concept]
- Montanide ISA-51/Peptide 946 melanoma vaccine [NCIt concept]
- Montanide ISA-51/Peptide 946 melanoma vaccine/Tetanus peptide melanoma vaccine [NCIt concept]
- Peptide 946 Melanoma Vaccine/QS21 [NCIt concept]
- Peptide 946 Melanoma Vaccine/QS21/Tetanus Peptide Melanoma Vaccine [NCIt concept]

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