Preferred Label : Iodine I 124 Monoclonal Antibody A33;
NCIt synonyms : I 124 Monoclonal Antibody A33; iodine I 124 MOAB A33;
NCIt definition : A radioimmunoconjugate of a humanized monoclonal antibody (MoAb) A33 labelled with
Iodine 124 (I-124). MoAb A33 recognizes A33 antigen, a 43 KDa transmembrane glycoprotein
of the immunoglobulin superfamily, highly and homogenously expressed in 95% of colorectal
cancer metastases, with only restricted expression in normal colonic mucosa. I-124
MoAb A33 delivers beta particle emitting I-124 nuclide directly to metastatic colorectal
tissues, thereby this agent could be used in kinetics studies or radioimmunotherapy.;
Origin ID : C2440;
UMLS CUI : C0677678;
Semantic type(s)
- concept_is_in_subset
