Preferred Label : IL-2 Plasmid DNA/Lipid Complex;
NCIt synonyms : Plasmid DNA IL-2 Lipid Complex; IL-2 Plasmid DNA/DMRIE/DOPE lipid complex; interleukin-2 DNA/lipid complex; IL-2 Plasmid DNA-Lipid Complex;
NCIt related terms : leuvectin;
NCIt definition : An immunotherapeutic agent consisting of a plasmid DNA encoding human Interleukin-2
(IL-2) complexed with a cationic lipid, 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl
ammonium bromide/dioleyl-phosphatidyl-ethanolamine (DMRIE/DOPE), in a 5:1 ratio. Due
to the lipophilic nature of this cation liposome complex, this gene transfer system
may improve the efficiency of introducing the IL-2 gene into the cells, thereby increasing
the production of IL-2 and inducing an immune response.;
Alternative definition : NCI-GLOSS: An agent that delivers the gene for interleukin-2 (IL-2) into cells to
increase production of IL-2 by the cells.;
Drug name : Leuvectin;
Molecule name : VCL-1102;
Codes from synonyms : CDR0000045548;
Origin ID : C2437;
UMLS CUI : C1527173;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- concept_is_in_subset
