Preferred Label : Monoclonal Antibody A1G4 Anti-Idiotype Vaccine;
NCIt synonyms : A1G4 anti-idiotype monoclonal antibody vaccine;
NCIt definition : An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside
GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma,
neuroblastoma, and other malignancies. GD2 is a highly expressed glycosphingolipid
by melanoma and other neuroectodermal tumors with only minimal expression on normal
tissues. Vaccination with anti-Id A1G4 MoAb may elicit cellular and humoral immune
responses against GD2 expression tumor cells.;
Origin ID : C2436;
UMLS CUI : C0677670;
Semantic type(s)
- concept_is_in_subset
