Iodine I 131 Monoclonal Antibody 3F8

Preferred Label : Iodine I 131 Monoclonal Antibody 3F8;

NCIt synonyms : iodine I 131 MOAB 3F8; I 131 Monoclonal Antibody 3F8; (131I)-3F8;

NCIt related terms : ANTI-GD2 MONOCLONAL ANTIBODY 3F8 I-131;

NCIt definition : A radioimmunoconjugate consisting of 3F8, a murine anti-GD2 ganglioside monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic properties. Using monoclonal antibody 3F8 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing GD2. GD2 is a ganglioside which is overexpressed in malignant melanoma, neuroblastoma, and small cell carcinoma of the lung. (NCI04);

UNII : 1CN551P1LM;

Details

Origin ID

C2431;

UMLS CUI

C0393072;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

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