Recombinant Adenovirus-p53 SCH-58500

Preferred Label : Recombinant Adenovirus-p53 SCH-58500;

NCIt synonyms : rAd/p53;

NCIt related terms : ACN53; recombinant adenovirus-p53; SCH-58500;

NCIt definition : A genetically-engineered adenovirus that contains the gene that encodes the human tumor-suppressor protein p53 with potential antineoplastic activity. Recombinant adenovirus-p53 SCH-58500 delivers p53 into tumor cells, which may result in p53-mediated cell cycle arrest and apoptosis.;

Alternative definition : NCI-GLOSS: A substance that has been studied in the treatment of some types of cancer. rAd/p53 is a weakened adenovirus that carries the p53 gene into tumor cells, causing them to die. It is a type of gene therapy.;

Molecule name : SCH-58500; SCH 58500;

Codes from synonyms : CDR0000413935; CDR0000413937; CDR0000539489; CDR0000045530;

Details

Origin ID

C2423;

UMLS CUI

C0393035;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Carboplatin/Paclitaxel/SCH-58500 [NCIt concept]
- Dexamethasone/Floxuridine/Leucovorin Calcium/SCH-58500 [NCIt concept]

Keyword's position in hierarchy(ies) :

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