Gimeracil - CISMeF

Preferred Label : Gimeracil;

NCIt synonyms : Chlorodihydroxypyridine; 5-Chloro-2,4-pyridinediol; CDHP;

NCIt definition : A pyridine derivative with antitumor activity. Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhibiting the enzyme dihydropyrimidine dehydrogenase causing decreased degradation of the fluoropyrimidines.;

UNII : UA8SE1325T;

InChIKey : ZPLQIPFOCGIIHV-UHFFFAOYSA-N;

CAS number : 103766-25-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 103766-25-2 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C5H4ClNO2;

Details

Origin ID

C2416;

UMLS CUI

C0535459;

CISMeF manual mappings
- Gimeracil (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Gimeracil (substance) [SNOMED CT concept]
- gimeracil [MeSH concept]
- gimeracil [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Chlorodihydroxypyridine/Potassium Oxonate/Tegafur [NCIt concept]

Keyword's position in hierarchy(ies) :

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