" /> Diethylhomospermine - CISMeF





Preferred Label : Diethylhomospermine;

NCIt synonyms : DEHOP; N(1),N(14)-bis(ethyl)homospermine; 1,14-bis(ethylamino)-5,10-diazatetradecane; DEHSPM; N1N14-diethylhomospermine; N1,N14-diethylhomospermine; N1N14-bis(ethyl)norspermine;

NCIt definition : A polyamine analogue with antiproliferative and potential anti-diarrheal activities. Diethylhomospermine (DEHSPM) antagonizes polyamine activity via NMDA receptor glutamine binding site, thereby modulating inotropic stasis and reducing stool volume (anti-diarrhea). However, due to the toxic effects from metabolites of DEHSP, other tetramine derivatives with less toxicity have been developed.;

UNII : 8G6X94GNHO;

CAS number : 119422-08-1;

Détails


Position du mot-clé dans l'(les) arborescence(s) : arborescence

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28/07/2025


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© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.

" /> Diethylhomospermine - CISMeF





Preferred Label : Diethylhomospermine;

NCIt synonyms : DEHOP; N(1),N(14)-bis(ethyl)homospermine; 1,14-bis(ethylamino)-5,10-diazatetradecane; DEHSPM; N1N14-diethylhomospermine; N1,N14-diethylhomospermine; N1N14-bis(ethyl)norspermine;

NCIt definition : A polyamine analogue with antiproliferative and potential anti-diarrheal activities. Diethylhomospermine (DEHSPM) antagonizes polyamine activity via NMDA receptor glutamine binding site, thereby modulating inotropic stasis and reducing stool volume (anti-diarrhea). However, due to the toxic effects from metabolites of DEHSP, other tetramine derivatives with less toxicity have been developed.;

UNII : 8G6X94GNHO;

CAS number : 119422-08-1;

Détails


Position du mot-clé dans l'(les) arborescence(s) : arborescence

Vous pouvez consulter :


Nous contacter.
28/07/2025


[Accueil] [Haut de page]

© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.