Preferred Label : Monoclonal Antibody A33;
NCIt synonyms : A33 Monoclonal Antibody; MoAb A33;
NCIt related terms : A33;
NCIt definition : A humanized monoclonal antibody directed against the human A33 antigen. Monoclonal
antibody A33 recognizes the human A33 antigen, a 43 KDa transmembrane glycoprotein
of the immunoglobulin superfamily, which is highly and homogenously expressed in 95%
of colorectal cancer metastases with only restricted expression in normal colonic
mucosa.;
Alternative definition : NCI-GLOSS: A type of monoclonal antibody used in cancer detection or therapy. Monoclonal
antibodies are laboratory-produced substances that can locate and bind to cancer cells.;
Codes from synonyms : CDR0000046722;
Origin ID : C2410;
UMLS CUI : C0392959;
Semantic type(s)
chemical_or_drug_has_mechanism_of_action
concept_is_in_subset