Preferred Label : Monoclonal Antibody Me1-14 F(ab')2;
NCIt synonyms : Me1-14 F(ab')2; Me1-14 F(ab')2 monoclonal antibody; MoAb Me1-14 F(ab')2; Monoclonal Antibody Me1-14 F ab 2;
NCIt definition : The F(ab)2 fragment of Me1-14, a murine IgG2a monoclonal antibody directed against
proteoglycan chondroitin sulfate-associated protein expressed by gliomas and melanomas.
By binding to proteoglycan chondroitin sulfate-associated protein, monoclonal antibody
Me1-14 F(ab')2 conjugated to a radioisotope may localize gliomas and melanomas when
used as a tracer in radioimaging applications; in radioimmunotherapeutic applications,
this agent conjugated to a radioisotope may be used to deliver targeted radiotoxicity
to these tumors.;
Origin ID : C2409;
UMLS CUI : C0392955;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
