Preferred Label : gp209-2M Antigen;
NCIt synonyms : antigen, gp209-2m;
NCIt related terms : gp209-2M;
NCIt definition : A modified peptide antigen derived from gp209, with potential immunomodulatory and
antineoplastic activities. gp209-2M antigen (IMDQVPFSV) has a methionine substitution
of threonine at position 2 of gp209 peptide (ITDQVPFSV), which is the immunogenic
epitope of human melanoma tumor glycoprotein gp100. Vaccination with this peptide
may evoke a cytotoxic T lymphocyte (CTL) response against tumor cells expression of
the gp100 antigen.;
Alternative definition : NCI-GLOSS: A peptide (short piece of protein) made from the tumor-specific antigen
gp100, and used to make vaccines being studied in the treatment of melanoma.;
Codes from synonyms : CDR0000386204;
Origin ID : C2406;
UMLS CUI : C0338352;
Semantic type(s)
- concept_is_in_subset
- is_component_of_chemotherapy_regimen
