" /> Boronophenylalanine-Fructose Complex - CISMeF





Preferred Label : Boronophenylalanine-Fructose Complex;

NCIt synonyms : p-Boronophenylalanine-Fructose Complex;

NCIt related terms : BPA-F;

NCIt definition : A boronated phenylalanine complexed with fructose to increase its solubility. When exposed to neutron irradiation, boronophenylalanine absorbs neutrons and self-destructs releasing short-range alpha radiation and 'recoil' lithium in tumor cells, resulting in alpha radiation-induced tumor cell death. This highly selective, localized radiotargeting of tumor cells, known as boron neutron capture therapy (BNCT), spares adjacent normal tissues.;

Alternative definition : NCI-GLOSS: A substance used in a type of radiation therapy called boron neutron capture therapy. BPA-F is injected into a vein, and becomes concentrated in tumor cells. The patient then receives radiation treatment with atomic particles called neutrons. The neutrons react with the boron in BPA-F, producing radioactive particles that kill the tumor cells without harming normal cells.;

Codes from synonyms : CDR0000531098; CDR0000322133;

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Keyword's position in hierarchy(ies) : arborescence

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12/05/2024


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