Rasburicase - CISMeF

Preferred Label : Rasburicase;

NCIt related terms : recombinant urate oxidase; Elitek; SR-29142; Urate Oxidase;

NCIt definition : A recombinant urate oxidase enzyme isolated from a genetically-modified strain of Saccharomyces cerevisiae. Urate oxidase catalyzes the oxidation of uric acid to the excretable metabolite allantoin, a molecule that is 5-10 times more water-soluble than uric acid. An enzyme that occurs endogenously in most mammals, urate oxidase is not found in humans. (NCI04);

Alternative definition : NCI-GLOSS: A drug used to treat high blood levels of uric acid in patients with leukemia, lymphoma, and other types of cancer who are receiving certain types of cancer treatment. It is also being studied in the treatment of other medical conditions. Elitek is a type of recombinant enzyme and a type of urate-lowering drug.;

UNII : 08GY9K1EUO;

CAS number : 134774-45-1;

Drug name : Elitek;

Molecule name : SR-29142; SR 29142;

NSC code : 721631;

Codes from synonyms : NSC0671264; CDR0000046055; CDR0000306513; CDR0000658361; CDR0000658362; 436;

Details

Origin ID

C2404;

UMLS CUI

C0937932;

Automatic exact mappings (from CISMeF team)
- Urate oxidase [ICD-11 Extension code]
- Urate oxidase (substance) [SNOMED CT concept]
- urate oxidase [SNOMED Notion]
- urate oxidase [MeSH Descriptor]
- urate oxidase [MeSH concept]
- urate oxidase [ATC Code]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing rasburicase (medicinal product) [SNOMED CT concept]
- Rasburicase (substance) [SNOMED CT concept]
- Recombinant urate oxidase (substance) [SNOMED CT concept]
- rasburicase [ATC Code]
- rasburicase [MeSH Supplementary Concept]
- rasburicase [MeSH concept]
Validated automatic mappings to BTNT
- rasburicase [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Cyclophosphamide/Methylprednisolone/Rasburicase/Vincristine [NCIt concept]
- Cyclophosphamide/Prednisone/Rasburicase/Vincristine [NCIt concept]

Keyword's position in hierarchy(ies) :

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