Preferred Label : GD2-KLH Vaccine;
NCIt synonyms : KLH-conjugated GD2 Ganglioside Vaccine; Ganglioside GD2-KLH;
NCIt definition : A cancer vaccine containing an epitope of glycosphingolipid GD2 conjugated with the
immunostimulant keyhole limpet hemocyanin (KLH), with potential antineoplastic activity.
The disialoganglioside GD2 is a tumor-associated antigen expressed on the surface
of several cancers, including neuroblastoma medulloblastomas, astrocytomas, melanomas,
small-cell lung cancer, osteosarcomas, and other soft tissue sarcomas. Vaccination
with GD2-KLH vaccine may elicit antibody production against cells expressing GD2 ganglioside,
thereby reducing tumor cell growth.;
Origin ID : C2400;
UMLS CUI : C0338229;
Semantic type(s)
- concept_is_in_subset
