" /> Liposomal Cytarabine - CISMeF





Preferred Label : Liposomal Cytarabine;

NCIt synonyms : Encapsulated Cytarabine; DepoFoam Encapsulated Cytarabine; Cytarabine Liposome; Cytarabine Liposomal; Liposomal Ara-C;

NCIt related terms : Depo-Cyt;

NCIt definition : A liposomal intrathecal formulation of the antimetabolite cytarabine. As an S-phase-specific antimetabolite, cytarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; the incorporation of cytarabine triphosphate into DNA appears to inhibit DNA polymerase and so DNA synthesis, resulting in cell death. (NCI04);

Alternative definition : NCI-GLOSS: A form of the anticancer drug cytarabine that is contained inside very tiny, fat-like particles. It may have fewer side effects and work better than cytarabine. It is used to treat lymphoma that has spread to the meninges (three thin layers of tissue that cover and protect the brain and spinal cord). It is also being studied in the treatment of other types of cancer. It is a type of antimetabolite.;

Drug name : DepoCyte; DepoCyt;

Molecule name : DTC 101;

NSC code : 715320;

Codes from synonyms : CDR0000579858; CDR0000579859; NSC0715320; CDR0000579860; 128;

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08/05/2024


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