Monoclonal Antibody 14G2A

Preferred Label : Monoclonal Antibody 14G2A;

NCIt synonyms : Antibody 14G2A, Monoclonal; 14G2A, monoclonal antibody; 14G2A; MoAb 14G2A;

NCIt related terms : MURINE MONOCLONAL ANTI-GD2 ANTIBODY 14G2A;

NCIt definition : A murine monoclonal antibody directed against the ganglioside GD2 with potential antineoplastic activity. Monoclonal antibody 14G2A binds to the ganglioside GD2 and induces antibody-dependent cell mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung. (NCI04);

UNII : TC4U60XS42;

NSC code : 624345;

Codes from synonyms : NSC0624345;

Details

Origin ID

C2368;

UMLS CUI

C0280838;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Interleukin-2/Monoclonal Antibody 14G2A [NCIt concept]
- Interleukin-2/Monoclonal Antibody 14G2A/Sargramostim [NCIt concept]

Keyword's position in hierarchy(ies) :

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