NCIt definition : Any antibiotic containing amino-modified sugars originally isolated from various Streptomyces
and Micromonospora species. Aminoglycoside antibiotics bind to the 16S RNA of the
bacterial 30S ribosomal subunit, inhibiting translation and protein synthesis. Aminoglycoside
use is associated with ototoxicity, neurotxicity and nephrotoxicity.;
Alternative definition : NCI-GLOSS: A family of antibiotics that works against many types of bacteria and includes
streptomycin, gentamicin, and neomycin. Aminoglycosides are used to treat bacterial
infections.;