NCIt related terms : Detoxepa; Hepalidine; 4-Thiazolidinecarboxylic Acid; Thioproline;
NCIt definition : A cyclic sulfur amino acid derivative with potential antineoplastic and antioxidant
activities. Acting on cellular membranes of malignant cells through an unknown mechanism,
timonacic may induce malignant cells to revert back to an untransformed state. This
agent may also restore contact inhibition, a phenomenon characterized by the paracrine
inhibition of mitosis following the formation of a critical cell mass, presumably
the result of cell-to-cell signal transfer. Timonacic may also produce antioxidant
effects secondary to its release of cysteine and restoration of glutathione concentrations.;