Preferred Label : Ovine Submaxillary Mucin;
NCIt synonyms : Ovine Sialomucin;
NCIt definition : A naturally occurring mucin glycoprotein. Ovine submaxillary mucin (OSM), extracted
from an ovine submaxillary gland, provides a rich source of the sialylated Tn antigen
(sTn), which is a carbohydrate antigen found on mucins of many epithelial tumors.
Vaccination with OSM may result in the production of antibodies as well as elicitation
of a cytotoxic T- lymphocyte (CTL) response against tumor cells expressing sTn, thereby
results in decreased tumor cell growth.;
Origin ID : C2350;
UMLS CUI : C0279238;
Semantic type(s)
- concept_is_in_subset
