" /> Aminoglutethimide - CISMeF





Preferred Label : Aminoglutethimide;

NCIt synonyms : alpha-(4-Aminophenyl)-alpha-ethylglutarimide; 3-Ethyl-3-(p-aminophenyl)-2,6-dioxopiperidine; Orimenten; 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione;

NCIt related terms : 2-(p-Aminophenyl)-2-ethylglutarimide; Ba-16038; Elipten;

NCIt definition : A synthetic derivative of the sedative and anticonvulsant glutethimide with anti-steroid properties. Originally used as an anticonvulsant, aminoglutethimide also blocks adrenal steroidogenesis by inhibiting the enzymatic conversion of cholesterol to pregnenolone. In addition, this agent blocks the peripheral aromatization of androgenic precursors to estrogens. Aminoglutethimide does not suppress ovarian estrogen production.;

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called nonsteroidal aromatase inhibitors. Aminoglutethimide is used to decrease the production of sex hormones (estrogen in women or testosterone in men) and suppress the growth of tumors that need sex hormones to grow.;

UNII : 0O54ZQ14I9;

InChIKey : ROBVIMPUHSLWNV-UHFFFAOYSA-N;

CAS number : 125-84-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 125-84-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Cytadren; Orimetene; Rodazol; Orimeten; Mamomit; Aminoblastin; Elipten;

Molecule name : BA-16038;

Chemical formula : C13H16N2O2;

NSC code : 330915;

ChEBI ID : CHEBI:2654;

Codes from synonyms : NSC0330915; 00407; CDR0000045170; 28;

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16/06/2024


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