" /> Glucocorticoid - CISMeF





Preferred Label : Glucocorticoid;

NCIt definition : A corticosteroid that supports a variety of cardiovascular, metabolic, immunologic, and homeostatic functions, and which binds specifically to the glucocorticoid receptor (GR; NR3C1). Glucocorticoid binding to GR leads to the transportation of the activated receptor-glucocorticoid complex to the nucleus, after which it binds to glucocorticoid response elements (GRE) and regulates the expression of GR-responsive genes.;

Alternative definition : NICHD: A group of corticosteroids that affect carbohydrate metabolism, inhibit corticotropin secretion, and possess pronounced anti-inflammatory activity.; NCI-GLOSS: A compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They may be naturally produced (hormones) or synthetic (drugs).;

ChEBI ID : CHEBI:24261;

Codes from synonyms : CDR0000045295;

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09/05/2025


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