Bleomycin Antibiotic

Preferred Label : Bleomycin Antibiotic;

NCIt synonyms : Bleomycins;

NCIt definition : A basic glycopeptide antineoplastic antibiotic isolated from Streptomyces verticillus. Bleomycin antibiotics form complexes with iron that react with molecular oxygen to produce superoxide and hydroxyl free radicals, causing single- and double-stranded breaks in DNA. These reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.;

NCI Metathesaurus CUI : CL448369;

ChEBI ID : CHEBI:22907;

Details

Origin ID

C2311;

UMLS CUI

C0005740;

False automatic mappings
- (111)In-bleomycin [MeSH concept]
See also inter- (CISMeF)
- Bleomycin [ACR pathology]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Antibiotic [UMLS semantic type]
UMLS correspondences (same concept)
- Bleomycin [ICD-11 Extension code]
- Bleomycin (substance) [SNOMED CT concept]
- Product containing bleomycin (medicinal product) [SNOMED CT concept]
- bleomycin [ATC Code]
- bleomycin [MeSH concept]
- bleomycin [MeSH Descriptor]
- bleomycin [SNOMED Notion]
Validated automatic mappings to BTNT
- bleomycin [ATC Code]
- bleomycin [MeSH Descriptor]
Validated automatic mappings to NTBT
- BLEOMYCIN [SMS substance]

Keyword's position in hierarchy(ies) :

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