Preferred Label : Cytokeratin-18 Staining Method;
NCIt synonyms : Cytokeratin 18 Staining Method; CK18 Staining Method; Keratin, Type I Cytoskeletal 18 Staining Method;
NCIt definition : An immunohistochemical technique to detect cytokeratin 18, an intermediate filament
protein, using monoclonal antibody to cytokeratin 18. Specific combinations of cytokeratin
peptides are associated with certain epithelial cells, and are therefore useful in
the characterization of poorly differentiated carcinoma. The antibody reacts with
a large number of epithelial cell types including many ductal and glandular epithelia.
The test is used as a clinically significant indicator in distinguishing carcinoma
from malignant tumors of non-epithelial origin, such as lymphoma, sarcoma, and melanoma.;
Origin ID : C23027;
UMLS CUI : C1527158;
Semantic type(s)
- related_to_genetic_biomarker
