Preferred Label : Cytokeratin-8 Staining Method;
NCIt synonyms : Cytokeratin 8 Staining Method; CK8 Staining Method; Keratin, Type II Cytoskeletal 8 Staining Method; KRT8 Staining Method;
NCIt definition : An immunohistochemical technique to detect cytokeratin 8, an intermediate filament
protein, using monoclonal antibody to cytokeratin 8. The antibody is useful in the
detection of adenocarcinomas, mesotheliomas, and certain squamous epithelia-derived
carcinomas. Specific combinations of cytokeratin peptides are associated with certain
epithelial cells, and are therefore useful in the characterization of poorly differentiated
carcinoma. The test is used as a clinically significant indicator in distinguishing
carcinoma from malignant tumors of non-epithelial origin, such as lymphoma, sarcoma,
and melanoma.;
Origin ID : C23026;
UMLS CUI : C1527157;
Semantic type(s)
- related_to_genetic_biomarker
