Inhibin - CISMeF

Preferred Label : Inhibin;

NCIt synonyms : Folliculostatin; Inhibin Hormone;

NCIt definition : Inhibins are peptide hormones, secreted by the follicular cells of the ovary and by the testis, that negatively regulate the synthesis and secretion of follicle stimulating hormone from the anterior pituitary. The detection of serum inhibins has been implicated in association with reproductive disorders, including infertility and ovarian cancers.;

NCIt note : Both inhibin A and inhibin B are heterodimers consisting of an alpha subunit and a beta A or beta B subunit linked by disulphide bonds. Both inhibins function as negative regulators for FSH synthesis and secretion. Furthermore, serum concentrations of inhibins transit from inhibin B to inhibin A dominance during menstrual cycle.;

CAS number : 57285-09-3;

Details

Origin ID

C2276;

UMLS CUI

C0021463;

Automatic exact mappings (from CISMeF team)
- Inhibin A [LOINC component]
- Inhibin A [MedDRA Preferred Term]
- Inhibin A (substance) [SNOMED CT concept]
- inhibin A [MeSH concept]
- inhibin A [MeSH Supplementary Concept]
- transforming growth factor beta receptor binding [GO term]
False automatic mappings
- Inhibin hormone (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
UMLS correspondences (same concept)
- Inhibin [LOINC component]
- Inhibin hormone (substance) [SNOMED CT concept]
- inhibin hormone [SNOMED Notion]
- inhibins [MeSH concept]
- inhibins [MeSH Descriptor]
gene_product_has_biochemical_function
- Peptide Hormone [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]
- Protein Secretion [NCIt concept]
- Reproduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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