Preferred Label : Y 90 Monoclonal Antibody M195;
NCIt synonyms : MOAB M195, yttrium Y 90; Yttrium Y 90 Monoclonal Antibody M195; monoclonal antibody M195, yttrium Y 90; Y 90 MoAb M195;
NCIt definition : A radioimmunoconjugate of humanized M195 monoclonal antibody (MoAb) conjugated with
isotope yttrium 90. MoAb M195 is reactive with the cell surface antigen CD33, a glycoprotein
found on myeloid leukemia blasts and early hematopoietic progenitor cells but not
on normal stem cells. This radioimmunoconjugate emits beta particles that causes cytotoxicity
in tumor cells and has both imaging and therapeutic uses.;
Origin ID : C2248;
UMLS CUI : C0879572;
Semantic type(s)
concept_is_in_subset