Preferred Label : PSA RNA-Pulsed Dendritic Cell Vaccine;
NCIt definition : An autologous dendritic cell vaccine with potential immunostimulatory activity. Dendritic
cells harvested from a prostate cancer patient are transfected with the mRNA encoding
for prostate specific antigen (PSA), a tumor marker secreted by prostatic epithelial
and ductal cells. When reintroduced back to the patient, these PSA RNA pulsed autologous
dendritic cells may elicit a cytotoxic T-cell (CTL) response against PSA-positive
prostate cancer cells.;
Origin ID : C2236;
UMLS CUI : C0879395;
Semantic type(s)
concept_is_in_subset