Imidazole Mustard

Preferred Label : Imidazole Mustard;

NCIt synonyms : TIC Mustard; 5-[3,3-Bis(2-Chloroethyl)-1-Triazeno]Imidazole-4-Carboxamide; BIC;

NCIt related terms : 5-(3,3-BIS(2-CHLORETHYL)-1-TRIAZENO)IMIDAZOLE-4-CARBOXAMIDE; 5-[3, 3-Bis(2-chloroethyl)-1-triazeno]imidazole-4-carboxamide; 5-[3, 3-Bis(2-chloroethyl)-1-triazeno]-imidazole-4-carboxamide;

NCIt definition : A synthetic derivative of imidazole with potent antineoplastic properties. Imidazole mustard alkylates DNA, preferentially at guanine residues, resulting in DNA interstrand crosslinks and inhibition of DNA replication and RNA and protein synthesis. (NCI04);

UNII : OY338X4M2P;

CAS number : 5034-77-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 5034-77-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

NSC code : 82196;

Codes from synonyms : NSC0082196;

Details

Origin ID

C2216;

UMLS CUI

C0063382;

Automatic exact mappings (from CISMeF team)
- Micro rna 155 [OMIM gene]
Currated CISMeF NLP mapping
- imidazole mustard [MeSH concept]
- imidazole mustard [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- imidazole mustard [MeSH concept]
- imidazole mustard [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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