" /> Sodium Borocaptate - CISMeF





Preferred Label : Sodium Borocaptate;

NCIt synonyms : Borocaptate Sodium;

NCIt related terms : BSH;

NCIt definition : A boron-carrying compound. After parenteral administration, sodium borocaptate accumulates preferentially in tumor cells. When exposed to neutron irradiation, borocaptate absorbs neutrons and self-destructs releasing short-range alpha radiation and 'recoil' lithium in tumor cells, resulting in alpha radiation-induced tumor cell death. This highly selective, localized radiotargeting of tumor cells, known as boron neutron capture therapy (BNCT), spares adjacent normal tissues. (NCI04);

Alternative definition : NCI-GLOSS: A substance used in a type of radiation therapy called boron neutron capture therapy. Sodium borocaptate is injected into a vein and becomes concentrated in tumor cells. The patient then receives radiation treatment with atomic particles called neutrons. The neutrons react with the boron in sodium borocaptate and make radioactive particles that kill the tumor cells without harming normal cells.;

CAS number : 80-17-1;

Drug name : Borocarpin;

NSC code : 643;

Codes from synonyms : CDR0000410742; CDR0000322233;

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06/05/2025


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