Bispecific Antibody MDX447

Preferred Label : Bispecific Antibody MDX447;

NCIt synonyms : BsAb MDX447;

NCIt definition : An antibody with potential antineoplastic activity. Specific for both the high-affinity immunoglobulin G (IgG) receptor CD64 and epidermal growth factor receptor (EGFR), bispecific antibody MDX447 may enhance cellular immune responses against EGFR positive cells, resulting in increased tumor cell lysis. (NCI04);

Molecule name : EMD 82633; MDX-447; MDX 447;

Details

Origin ID

C2207;

UMLS CUI

C0879492;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Bispecific Antibody MDX447/Lymphokine-Activated Killer Cells [NCIt concept]

Keyword's position in hierarchy(ies) :

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