Preferred Label : Acridine Carboxamide;
NCIt synonyms : N-(2-(Dimehtylamino)ethyl)acridine-4-carboxamide;
NCIt related terms : DACA;
NCIt definition : A tricyclic acridine-based (or carboxamide-based) drug with dual topoisomerase inhibitor
and potential antineoplastic activities. Acridine carboxamide inhibits both topoisomerases
I and II and intercalates into DNA, resulting in DNA damage, the disruption of DNA
repair and replication, the inhibition of RNA and protein synthesis, and cell death.;
Alternative definition : NCI-GLOSS: A substance being studied in the treatment of cancer. It is a type of topoisomerase
inhibitor.;
UNII : 0N3V8R4E13;
InChIKey : XBGNERSKEKDZDS-UHFFFAOYSA-N;
CAS number : 89459-25-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 89459-25-6
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G-SRS /a ;
Molecule name : XR5000; SN 22995;
Codes from synonyms : CDR0000044849; CDR0000044885;
Origin ID : C2203;
UMLS CUI : C0919282;
Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
