Alternative definition : MMHCC: Variant of Diffuse Astrocytoma characterized by the presence of a conspicuous,
though variable, fraction of Gemistocytes --round to oval astrocytes with abundant,
glassy, non-fibrillary cytoplasm which appears to displace the dark, angulated nucleus
to the periphery of the cell. To make the diagnosis of Gemistocytic Astrocytoma, gemistocytes
should amount to more than approximately 20% of all tumor cells (fewer is considered
a fibrillary astrocytoma). Gemistocytes are strongly GFAP positive.;