NCIt definition : A mineralocorticoid hormone produced by aldosterone synthase (CYP11B2) in the zona
glomerulosa of the adrenal cortex. Aldosterone binds to mineralocorticoid receptors
(MR; NR3C2) and MR-aldosterone complexes regulate the expression of genes involved
in the retention of sodium, the secretion of potassium, and water reabsorption, all
of which may result increased blood pressure.;
Alternative definition : NCI-GLOSS: A steroid hormone made by the adrenal cortex (the outer layer of the adrenal
gland). It helps control the balance of water and salts in the kidney by keeping sodium
in and releasing potassium from the body. Too much aldosterone can cause high blood
pressure and a build-up of fluid in body tissues. Aldosterone is a type of mineralocorticoid
hormone.;