Cyclin-Dependent Kinase Inhibitor

Preferred Label : Cyclin-Dependent Kinase Inhibitor;

NCIt synonyms : CDK Inhibitor; CDKI; Cyclin-Dependent Kinase Inhibitor Drug;

NCIt definition : Any substance that inhibits cyclin-dependent kinase (CDK), an enzyme that catalyzes the addition of a phosphate group to a protein in the cell cycle regulation pathway. Inhibition of cyclin-dependent kinase results in cell cycle arrest and apoptosis.;

Details

Origin ID

C2185;

UMLS CUI

C1511576;

Automatic exact mappings (from CISMeF team)
- cyclin dependent kinase inhibitor 3 [HGNC gene]
- cyclin-dependent protein serine/threonine kinase inhibitor activity [GO term]
- negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO term]
Manual BTNT mappings - CISMeF
- Cyclin-dependent kinase (CDK) inhibitors [ATC Code]
See also inter- (CISMeF)
- cyclin-dependent kinase inhibitor proteins [MeSH Descriptor]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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