Malignant Basal Cell Tumor of the Mouse Skin - CISMeF
Malignant Basal Cell Tumor of the Mouse SkinNCIt concept
Preferred Label : Malignant Basal Cell Tumor of the Mouse Skin;
Alternative definition : MMHCC: A cutaneous neoplasm composed of cells with basaloid cytology that does not
exhibit significant follicular differentiation and that is locally invasive or metastatic.
Strict diagnostic criteria should be applied for this rare murine tumor. Sheets of
basaloid tumor cells with a well formed peripheral palisade and numerous apoptotic
cells and mitotic figures should be present. Invasion of individual tumor nests is
a supportive feature. Most tumors of this type do not appear to arise from the follicular
epithelium in mice and do not the extensive follicular differentiation of the basaloid
follicular neoplasms listed below. The relationship of malignant basal cell tumor
and basaloid follicular neoplasms with human basal cell carcinomas is not well understood
at present..;